The global epidemic of new crown pneumonia continues to arouse people's attention. At the same time, immunity and health have become the primary considerations for consumers.

Innova Market Insight’s consumer survey shows that after the outbreak of the new crown epidemic, one in four people in the world have become more concerned about their immunity. The most significant growth is the millennial generation (26 to 35 years old) and the X generation (36 to 45 years old). These relatively young people are more concerned about immune health, which means that the consumption enthusiasm of related products will not decline in the short term.

Data source: Innova Market Insight (ID: InnovaChina)

It is often said that people with high immunity are not easy to get sick. So what is immunity and where does it come from?

Immunity refers to a person's ability to resist external viruses, mainly from the body's own immune system. The immune system is described as the guardian of the human body. On the one hand, it can resist all harmful bacteria and viruses outside the body, and it can also fight against the bacteria and viruses that enter the body to ensure the normal operation of human physiological metabolism.

Recently, researchers from the University of Washington in the United States published an article titled "The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis" on Cell. This study uses the microbiome, metabolome, and single-cell transcription. Group and other technologies have revealed how the intestinal flora can inhibit alphavirus infection through the "gut-immune axis" regulation pathway.

The "gut-immune axis" has gradually become a research hotspot in major universities, and consumers also believe that having a healthy gut or microbiome is the most important for achieving immune health.

Prevent disease, start now

When there is a problem with the immune system, the body's resistance to external bacteria and viruses decreases, which will lead to the occurrence of various diseases. According to medical research, more than 90% of human diseases are related to immune disorders.

As the most important digestive organ of the human body, the intestine is also an important organ of the immune system. The most easily invaded part of pathogenic microorganisms is the oral cavity, and the oral cavity is connected with the intestines, and the imbalance of the intestinal flora can easily cause the production of many diseases, so the immune function of the intestinal can not be ignored.

Image source: pixbay

There are many ways to improve your own immunity, such as strengthening sports, supplementing vitamins, and ensuring adequate sleep. Among them, a reasonable dietary supplement is the quickest and simplest method.

FOS-the guardian of improved immunity

FOS is a nutritional supplement with typical prebiotic effects recognized by European EFSA and US FDA. Because of its excellent physical and chemical properties, health benefits and clear chemical structure, it has been recognized as a function in my country Sexual food ingredients are widely used in industries such as food, feed, beauty and hair care, biscuits, and infant milk products.

FOS have a wide range of functions. They can not only promote the proliferation of beneficial bacteria such as bifidobacteria in the intestine, but also increase the body's absorption rate of mineral elements, improve lipid metabolism, and enhance the body's immunity.

Japanese scholar Shinji Jinno ^[1] studied the effect of adding kestose (the main component of FOS) to the diet on the level of immunoglobulin (IgA) in mouse milk through animal experiments. Mice during pregnancy and lactation were fed a diet with or without 5% kestose to detect the level of IgA in mouse milk 7 and 14 days after delivery. The results showed that compared with the control group, the IgA content in the milk of the mice consuming kestose increased significantly after 7 days and 14 days. It can be seen that supplementation of kestose in the diet of pregnant and lactating mice will increase the level of IgA in the milk.

Akira holono ^[2] tested the immune response of the intestinal mucosa by gavage 0-7.5% FOS in BALBW/c mice for 6 weeks, and explored the effect of oral oligofructose on the immune function. The results showed that the IgA value in the feces of rats in the 2.5% FOS group was significantly increased. Under the stimulation of FOS, the immunoglobulin (IgA) secreted by PP cells was up-regulated in a dose-dependent manner, and the interferon-g (IFN-g) and interleukin (IL) produced by CD4+ T cells derived from PP cells 10 It also increased in a dose-dependent manner, and IL-5 and IL-6 were also highly secreted. In contrast, FOS inhibits the secretion of serum IgG1. This indicates that supplementation with FOS can change the intestinal environment of BALBW/c mice, leading to an up-regulation of IgA secretion in intestinal mucosal PP cells.

FOS can improve the body's immunity, which can also be achieved through the proliferation of beneficial intestinal bacteria in the body. As a large number of components in the human body, the intestinal flora has a complex relationship with the human immune system. Studies have shown that obligate anaerobic bacteria, such as bifidobacteria, distributed on the inner side of the intestine can form a bacterial membrane on the surface of the intestinal epithelium to enhance intestinal defenses through competition and inhibit the impact of potential exogenous pathogenic bacteria in the digestive tract on the intestines. Adhesion and colonization of epithelial cells.

Long Xiaolei ^[3] studied the effect of FOS oral liquid on human intestinal flora. The 102 subjects were randomly divided into a test group and a control group. They took oligofructose oral liquid or placebo for 14 consecutive days, collected stool before and after the sample, and observed the changes in the number of intestinal flora of the population before and after the test. The results showed that the number of bifidobacteria and lactobacilli in the intestinal tract increased by 0.22 and 0.29 CFU/g respectively after the test in the food group. The FOS oral liquid has the effect of improving the intestinal flora, is conducive to regulating the human body's microecological balance, and enhancing the body's immunity.

"So True's FOS"— to help you get a smoother path to immunity

As a high-quality prebiotic, the FOS product of Shandong Starlight So True Biological Technology Co., Ltd. adopts self-invented patented technology, uses sucrose as raw material, and is catalyzed by fructosyltransferase. So True's FOS product has excellent characteristics such as good fluidity, low water activity, high purity, and excellent probiotic functions. It is the best choice for improving the body's immunity.

References:

[1]Rong-Fu, Wang, Marjorie, et al. Design and evaluation of oligonucleotide-microarray method for the detection of human intestinal bacteria in fecal samples[J]. FEMS Microbiology Letters, 2002.

[2] Hosono A, Ozawa A, Kato R, et al. Dietary Fructooligosaccharides Induce Immunoregulation of Intestinal IgA Secretion by Murine Peyer's Patch Cells[J]. Journal of the Agricultural Chemical Society of Japan, 2003, 67(4):758- 764.

[3] Long Xiaolei, Li Zimin, Zhou Yuechan, Yi Chuanzhu, Hu Yuming. The effect of oligofructose oral liquid on human intestinal flora[J]. Journal of Applied Preventive Medicine, 2016, 22(03): 227-229.